
Cases range from mild–showing minor body language changes during the owner’s departure–to severe–dogs injuring themselves and destroying the home by chewing through drywall and jumping out windows. Regardless of severity, it is important to obtain a diagnosis and begin treatment to not only keep these patients safe from anxiety and self-injury and the family’s home undamaged, but also to keep intact the human-animal bond.
Beginning Treatment
Obtaining a diagnosis from a veterinarian is the first step toward treatment. The patient should be medically worked up and assessed as there may be underlying medical or anxiety-related concerns that will exacerbate this issue. After a medical workup, the veterinary medical team can assist the owner by reviewing the veterinarian’s treatment plan, including safety, prevention, management, and behavioral therapy.
Depending on the diagnosis and severity of the problem, the veterinarian may also prescribe medications to reduce patient stress and anxiety during departures. The veterinary medical team can discuss trialing medications and potential side effects on a case-by-case basis.
Eyes in the Sky: Videotaping Alone Time
With advances in technology, we have a variety of ways to watch pets who are home alone. For a potential separation-related issue, it’s vital to recommend that the client have video and camera accessibility to the pet during departures. Not only can we evaluate the pet’s distress levels during departures, but this can be an important tool for the veterinarian in determining a diagnosis. We may find that the patient is not always distressed during departures and that an outside stimulus is causing the dog to panic. The veterinarian would diagnose and treat this problem very differently.
Lonely No More: Avoiding Alone Time
For severe cases where self-injury and destruction in the home are concerns, the veterinarian may recommend avoiding leaving the pet alone. This is not a long-term fix but can help keep the pet safe during treatment and behavior modification. Owners may have a pet sitter stay at the home during work hours or use boarding facilities or daycares.
Changing the Meaning of Time Alone
Part of behavioral therapy for separation distress is to change the way the patient feels about being alone. A great way to start this process is with high-value food for the patient to enjoy during departures. A lickable item is easy to ingest and easy for a pet to focus on when distressed. Think peanut butter, cream cheese, spray cheese, cheese spread, canned pumpkin, yogurt, mashed potatoes, and canned dog food. Food-enrichment items such as food bowl mazes, Kongs, plates, bowls, and muffin tins can be used to administer these treats.
Another benefit of using food is that we can monitor the patient’s stress level. If a patient is a peanut butter Kong fanatic when the owner is home, but that same patient will not touch the peanut butter during a departure, this tells us the patient is too stressed and anxious to enjoy the food enrichment offered. Relay this information to the veterinarian so the treatment plan can be altered.
Long-Term Success
Medications can help to reduce the patient’s anxiety, but behavioral therapy is crucial to long-term success. A treatment plan should include the following:
- Shaping relaxed and independent behaviors: The goal is to teach the patient that calm, cool, collected behavior brings reinforcement. Positive reinforcement and clicker training can be helpful in implementing this step.
- Creating a non-stressful and consistent departure routine to reduce overall anxiety: Instruct the owner to start working on short departures with the pet showing limited signs of stress and anxiety. The home will be set up in a consistent, predictable way while food enrichment is offered. “Safety cues” (bandanas on the door, scents, etc.) can be added to communicate to the pet that the owner will be back momentarily.
- Changing the meaning of current departure cues: Departure cues are common indicators that owners will be leaving the home: putting on shoes, picking up keys/purse, or putting on a jacket. Owners should perform these cues during times when departures are not taking place. With repeated exposure, the pet will not always associate these cues with departures. Positive reinforcement can also be added in with the cue to create an even more positive association.
Medications and Supplements
Combining behavior therapy with psychotropic medications and supplements can improve the prognosis for separation anxiety. Primary medications such as fluoxetine (Reconcile) and clomipramine (Clomicalm) are licensed for use for in dogs with separation anxiety.
Other as-needed, event, or triage medications can be used for the departure itself to help reduce panic and stress. Some of these medications include Trazodone, Clonidine, or benzodiazepine(s) and are off-label use. The prescribing veterinarian will select these medications on a case-by-case basis. Pheromones (Adaptil) and supplements such as Zylkene (milk casein), and Anxitane (L-theanine) may also be suggested.
Consider referring severe cases to a veterinary behaviorist to help prevent the problem from becoming worse. For more information about separation anxiety, see or refer clients to the videos on separation anxiety at FearFreeHappyHomes.com.
This article was reviewed/edited by board-certified veterinary behaviorist Dr. Kenneth Martin and/or veterinary technician specialist in behavior Debbie Martin, LVT.


When Fiona first came to us at Gamble Pet Clinic, an examination without a fearful reaction from her was impossible. An attack by another dog at a young age had caused her to be anxious and nervous ever since. She had been muzzled at every veterinary clinic since her attack until coming to Gamble Pet Clinic. She was fearful initially, trying to nip at the doctor and staff when they attempted to examine her.
I took the Fear Free course. It was interesting and useful. I’m now working with two local veterinary offices who found me through the Fear Free website.
Sal was brought to us to establish why he had been having chronic vomiting and diarrhea. When I approached him in the lobby, he immediately pinned his ears and retreated under the couch. We brought him into an exam room, and he warmed up a bit but was still wary. Mom and Dad mentioned that in the past at other clinics he was taken to “the back” for vaccines and they could hear him vocalizing from the exam room.




Hunter, a 2-year-old mixed breed, enjoys looking out the windows in the lobby of our clinic. By starting his visit there, asking his mom questions and listening to his heart and lungs, we can make sure he is comfortable enough to continue his exam in the exam room. But it was a different story when he first came in almost two years ago. Because of a previous frightening experience at another clinic, he was wary of us and the handling and procedures being done. He would bare his teeth, growl, and even try to nip at Dr. Gamble’s hands when she tried to touch him. Through consistent Victory Visits, pre-visit training and medications, and desensitization to areas where vaccines and other needle pokes are typically given, we are now able to provide him and his owner with a comfortable and rewarding experience every time he is in. Now he sits patiently and lets Dr. Gamble examine him—with the help of some cheese and marshmallows, not to mention smears of his favorite treats, peanut butter and canned food. During Hunter’s victory visits, we commonly work on the desensitization process without actually following through with an injection. “Happy visits, along with some training classes and behavior work on our part, have made a world of difference to Hunter,” writes his owner, Beth. “Hunter is now excited to see Emily, Heather, Dr. Gamble, and many other staff members as soon as he walks through the front door. He is a much happier dog at the vet thanks to Gamble Pet Clinic’s Fear Free work.”
Recently, there was an event called Woof Fest held during a downtown pub crawl. Our clinic sponsored “Dog Trivia,” and I focused the questions on a pet’s emotional health, such as “Is this dog’s body language calm or stressed?” and “A dog wagging their tail is always happy. True or False?” Hundreds of people played our trivia game, and it was such a rewarding experience to educate the public on the topic.
Sammy had grown up in a hoarding situation and was fearful at the time of his adoption. Unless he was sedated, the six-year-old dog would bark and lunge or even eliminate from fear during veterinary visits. A prescription for an SSRI helped and the team tried additional medications at different doses, but Sammy would push through the medications and continue to show fear aggression. At first, he was unable to generalize that humans weren’t scary, so it was important for him to see the same person at the hospital on each visit. That wasn’t easy, but eventually the right person came along who was able to take the time and effort for Sammy to become comfortable. It took six months of Victory Visits spent eating chicken, practicing chin rests and lying on his side, and undergoing desensitization to having his leg shaved, the scent of alcohol, application of a topical product for numbness, and the pretend poke of a needle, but in July Sammy underwent his first successful blood draw. Now we are routinely doing happy visits to keep the momentum going.
Bruno is a goofy 8-year-old Bull Arab Cross (a type of Australian working dog). He has always been very friendly at the vet, but once pats stopped and the examination started, he would become suspicious and communicate his discomfort with aggressive behavior. Fortunately, Bruno’s owner has been committed to training. They had private training sessions and attended a Ready, Vet, Go! course. As part of Bruno’s training we incorporated a lot of owner education on subtle body language changes, as well as start and stop cues for Bruno. Bruno was trained with a sustained chin target, using a towel on a chair, as his start cue, meaning “I’m ready for procedure.” If he lifted his head, we immediately stopped the procedure. Bruno was also trained to be comfortable with a Baskerville Ultra Muzzle. We spent time teaching Bruno specific body parts such as tail, ear, and scruff, so that he knew what was about to happen. Over time we were able to pair several good vet clinic experiences (training on a Sunday in clinic) with lots of his fave foods, body scratches, and games. We also introduced veterinary equipment, including syringes, blunt needle, alcohol swabs, and stethoscope. When we weren’t actively training, he was taught a default “chill” behavior and rewarded for relaxed head, tail, and big breaths. He had several socialization visits at the vet, and when he required surgery for a lump removal we did practice runs with pre-visit medication to see what would work best for him. A planned course of action on admission saw him anesthetized as soon as possible to limit buildup of anxiety. Since then Bruno has had further training sessions and socializing vet visits. Recently he had his vaccinations and we were able to give his injection without any restraint by utilizing his muzzle and target training. Bruno is a great example of what teamwork can achieve when you have a committed owner and a Fear Free-trained vet and trainer, not to mention a goofy, food-motivated dog!
